Endocrine Abstracts

Objective: Many patients receiving thyroid hormone replacement therapy complain of persistent lethargy and related symptoms even with normal TSH levels. However, it remains unclear whether this is related to thyroxine replacement or coincidental psychological morbidity.Design: Using general practice computer records, 961 patients on thyroxine (minimum of 4 months) and their age- and sex-matched controls were identified and sent a two-page questionnaire, comprising the shor...